Research & Development

For more precise information on the programs of the I-Stem research teams and technological platforms, 
please go to the listed pages.

Muscular diseases

Christian Pinset

Motoneuron diseases

Cécile Martinat


Christelle Monville

Neuroplasticity and therapeutic

Alexandra Benchoua


Christine Baldeschi

Wolfram syndrome

Lætitia Aubry

Projects management

Marc Peschanski

Progeria project

Xavier Nissan


Xavier Nissan

Myelinated fibre

Nicolas Tricaud

Research Teams working on projects targeting specific therapeutic goals

The I-Stem laboratory is an institution dedicated to the exploration of potential therapeutic applications of human ES and iPS cells and therefore, is rather a scientific R&D center focusing on translational research. The therapeutic objective is a constant preoccupation which translates into the organisation of teams focused on specific aims and timelines. Such an organisation enables us to test the “feasibility” of the scientific process since each calendar displays benchmarks, with specific objectives in specified periods.

The current scientific programs of I-Stem

The primary focus of the research teams has been targeting several monogenic diseases. These diseases were chosen primarily as scientific opportunities and their number is continuously expanding as the I-Stem Institute matures and increases in size.

As concerns more precisely pathological modelling and pharmacological approaches, the ambition of I-Stem is to develop a research technology capable of covering all aspects of discovery and development of therapeutic molecules for pre-clinical trials in monogenic diseases, until candidate compounds are identified.

Many industrial and academic partnerships have already been established.