Publications scientifiques 2021

 

Epitope spreading toward wild-type melanocyte-lineage antigens rescues suboptimal immune checkpoint blockade responses.

Lo JA, Kawakubo M, Juneja VR, Su MY, Erlich TH, LaFleur MW, Kemeny LV, Rashid M, Malehmir M, Rabi SA, Raghavan R, Allouche J, Kasumova G, Frederick DT, Pauken KE, Weng QY, Pereira da Silva M, Xu Y, van der Sande AAJ, Silkworth W, Roider E, Browne EP, Lieb DJ, Wang B, Garraway LA, Wu CJ, Flaherty KT, Brinckerhoff CE, Mullins DW, Adams DJ, Hacohen N, Hoang MP, Boland GM, Freeman GJ, Sharpe AH, Manstein D, Fisher DE. SSci Transl Med. 2021 Feb 17;13(581):eabd8636. doi: 10.1126/scitranslmed.abd8636.

 

 

Human iPSC-derived neurons reveal early developmental alteration of neurite outgrowth in the late-occurring neurodegenerative Wolfram syndrome.

Pourtoy-Brasselet S, Sciauvaud A, Boza-Moran MG, Cailleret M, Jarrige M, Polvèche H, Polentes J, Chevet E, Martinat C, Peschanski M, Aubry L. Am J Hum Genet. 2021 Nov 4;108(11):2171-2185. doi: 10.1016/j.ajhg.2021.10.001. Epub 2021 Oct 25. PMID: 34699745.

 

 

The Future of Regenerative Medicine: Cell Therapy Using Pluripotent Stem Cells and Acellular Therapies Based on Extracellular Vesicles.

Jarrige M, Frank E, Herardot E, Martineau S, Darle A, Benabides M, Domingues S, Chose O, Habeler W, Lorant J, Baldeschi C, Martinat C, Monville C, Morizur L, Ben M’Barek K. Cells. 2021 Jan 27;10(2):240. doi: 10.3390/cells10020240 . PMID: 33513719

 

 

Contribution of Human Pluripotent Stem Cell-Based Models to Drug Discovery for Neurological Disorders.

Benchoua A, Lasbareilles M, Tournois J.Cells. 2021 Nov 24;10(12):3290. doi: 10.3390/cells10123290. PMID: 34943799

 

 

CRISPR gene editing in pluripotent stem cells reveals the function of MBNL proteins during human in vitro myogenesis.

Mérien A, Tahraoui-Bories J, Cailleret M, Dupont JB, Leteur C, Polentes J, Carteron A, Polvèche H, Concordet JP, Pinset C, Jarrige M, Furling D, Martinat C. Hum Mol Genet. 2021 Dec 17;31(1):41-56. doi: 10.1093/hmg/ddab218. PMID: 34312665

 

 

SISTEMA: A large and standardized collection of transcriptome data sets for human pluripotent stem cell research.

Jarrige M, Polvèche H, Carteron A, Janczarski S, Peschanski M, Auboeuf D, Martinat C. iScience. 2021 Jun 24;24(7):102767. doi: 10.1016/j.isci.2021.102767. eCollection 2021 Jul 23. PMID: 34278269

 

 

Exosomes: Multi-faceted natural intercellular messengers as new candidates for the treatment of myopathies?

Bayer-Wildberger A, Lorant J, Vilquin JT. Med Sci (Paris). 2021 Nov;37 Hors série n° 1:44-45. doi: 10.1051/medsci/2021192. Epub 2021 Dec 8. PMID: 34878395

 

 

Optogenetically controlled human functional motor endplate for testing botulinum neurotoxins.

de Lamotte JD, Polentes J, Roussange F, Lesueur L, Feurgard P, Perrier A, Nicoleau C, Martinat C. (2021). Stem cell research & therapy 12: 599. 10.1186/s13287-021-02665-3 . PMID: 34865655

 

 

Myogenesis modelled by human pluripotent stem cells: a multi-omic study of Duchenne myopathy early onset.

Mournetas V, Massouridès E, Dupont JB, Kornobis E, Polvèche H, Jarrige M, Dorval ARL, Gosselin MRF, Manousopoulou A, Garbis SD, Górecki DC, Pinset C. J Cachexia Sarcopenia Muscle. 2021 Feb;12(1):209-232. doi: 10.1002/jcsm.12665. Epub 2021 Feb 14. PMID: 33586340

 

 

AAV2/9-mediated silencing of PMP22 prevents the development of pathological features in a rat model of Charcot-Marie-Tooth disease 1 A.

Gautier B, Hajjar H, Soares S, Berthelot J, Deck M, Abbou S, Campbell G, Ceprian M, Gonzalez S, Fovet CM, Schütza V, Jouvenel A, Rivat C, Zerah M, François V, Le Guiner C, Aubourg P, Fledrich R, Tricaud N. Nat Commun. 2021 Apr 21;12(1):2356. doi: 10.1038/s41467-021-22593-3. PMID: 33883545